Quaternary Analytical System by Sartorius

The PATfix analytical quaternary system is an on-site tool, assisting process developers of innovative gene therapies in obtaining immediate feedback on their current process status. This facilitates faster iteration and process optimization, leading to improved purities and higher recoveries. The Sartorius analytical system offers modality-specific analysis and in-process control for gene therapy and vaccine products. Engineered to leverage the capabilities of CIMac analytical monolithic columns, the PATfix delivers swift, high-resolution runs. Operation with diverse detector types ensures rich analyses, even with intricate samples. The user-friendly PATfix software simplifies data processing, visualization, and sharing.

• Rapid, high-resolution analysis for large biomolecules
• Reduce time, cost, and labor compared to traditional methods
• Speed up process development and optimization
• Ensure production runs with real-time feedback
• Precise and consistent control of complex gradients via conductivity and pH monitoring
• Durable contact materials resistant to bio-buffers and CIP
• Minimal dead volume and path lengths for high resolution
• Unique CIMac monolithic columns for 'fingerprint' analysis, separation, and quantification
• Available in 19 different chemistries
• Simple sample preparation with low consumption
• Easily apply analytical insights to preparative chromatography for simplified scale-up
• CFR Part 11 compliant software for easy data processing, visualization, and sharing
• Secure data access from anywhere with server-client approach
• Centralized database for chromatograms from multiple runs and systems
• Effortlessly share interactive results with stakeholders